甄淑君（Shu Jun Zhen）

甄淑君

教授 博导 国家优秀青年科学基金获得者 重庆市学术技术带头人

个人简介

于2006年在西南大学获得环境科学学士学位，2011年在西南大学获得分析化学博士学位，2011年留校任教，2013年12月至2014年12月在美国德克萨斯大学奥斯汀分校访学，2014年晋升副教授，2021年晋升教授。到目前为止，以第一作者或通讯作者身份在Angew. Chem. Int. Ed.、ACS Nano、Adv. Funct. Mater.、Anal. Chem.、Small等期刊上发表学术论文70多篇，授权专利4项。获重庆市自然科学奖一等奖（排名第四）、重庆市优秀博士学位论文、 西南大学第十一届教师课堂教学比赛二等奖等奖励，获评化学“101计划”骨干教师、西南大学优秀本科生班主任、西南大学优秀研究生导师、西南大学优秀教师、2021年第七届中国国际“互联网+”大学生创新创业大赛重庆赛区选拔赛高教主赛道优秀创新创业导师等荣誉称号。近年来，获得国家优秀青年科学基金、国家自然科学基金面上项目（2项）、青年基金、国家重点研发计划子课题、重庆市基础与前沿研究重点项目、一般项目、重庆市自然科学基金面上项目、教育部新教师基金、中央高校基本科研业务费（重点发展项目、人才团队项目、重点项目、一般项目）等科研基金的资助。

联系方式

邮箱：zsj@swu.edu.cn

研究方向

光谱分析

代表性论文

1.Chen, W. T.; Li, Y. T.; Mao, K.; Zou, H. Y.; Zhan, L.; Huang, C. Z.*; Zhen, S. J.* Efficient Synthesis of Chiral Selenium Nano-Hexagonal Prisms Through Chiral Crystallization for Enantioselective Photoreduction. Adv. Funct. Mater. 2025, e26520.

2.Cao, L. P.; Huang, J.*; Hu, C.; Li, C. M.; Zhan, L.; Zhen, S. J.*; Huang C. Z.* Self-Assembly of DNA Nanoflares in Mitochondria for Sensitive In Situ Imaging of Cancer Markers. ACS Nano 2025, 19, 19918−19926.

3.Zang, H.; Wang, D. M.; Dai, W. J.; Chen, L.; Wang, Y. T.; Wang, Q.; Wang, Q.; Chen, G. X.; Li, J. J.; Xie, J. L.; Zou, H. Y.; Huang, C. Z.*; Li, Y. F.*; Zhen, S. J.* Highly Active Oxygen Evolution Reaction of NiMoO4 Sub-1 nm Nanowires Boosts Luminol Electrochemiluminescence. Small 2025, 21, 2407321.

4.Wang, Y. T.; Chen, G. H.; Wang, Q.; Zang, H.; Wang, Q.; Li, Y. F.; Zou, H. Y.; Zhan, L.; Xie, J. W.*; Huang, C. Z.*; Zhen, S. J.* Ultra-Fast Degradation of Mustard Gas Simulant by Titanium Dioxide-Phosphomolybdic Acid Sub-1 nm Nanobelts. Small 2025, 21, 2407980.

5.Li, C. H.; Xie, J. L.; Men, C.; Liu, L.; Huang, C. Z.; Li, C. M.*; Zhen, S. J.* Precise Delivery of Ricin A‑Chain and Photosensitizer by Aptamer-Functionalized Liposome for Targeted Chemo-Photodynamic Synergistic Therapy. ACS Materials Lett. 2024, 6, 2050−2058.

6.Xie, J. L.; Xie, T. J.; Luo, Y. J.; Mao, K.; Huang, C. Z.; Li, Y. F.; Zhen, S. J.* Octopus-like DNA nanostructure coupled with graphene oxide enhanced fluorescence anisotropy for hepatitis B virus DNA detection. Chin. Chem. Lett. 2024, 35, 109137.

7.Li, C.; Lv, W.; Yang, F.; Li, C.; Huang, C.*; Zhen, S.* Logic Control of Directional Long-Range Resonance Energy Transfer On 2D DNA Nanosheet. Small 2023, 2301811.

8.Lv, W. Y.; Li, L. L.; Guan, C. Y.; Li, C. M.; Huang, C. Z.*; Zhen, S. J.* Rational Design of Cascade DNA System for Signal Amplification. Anal. Chem. 2023, 95, 7603−7610.

9.Xie, T. J.; Xie, J. L.; Luo, Y. J.; Mao, K.; Huang, C. Z.; Li, Y. F.; Zhen, S. J.* CRISPR-Cas12a Coupled with DNA Nanosheet-Amplified Fluorescence Anisotropy for Sensitive Detection of Biomolecules. Anal. Chem. 2023, 95, 7237−7243.

10.Cao, L. P.; Li, C. M.; Zhen, S. J.*; Huang, C. Z.* A General Signal Amplifier of Self-Assembled DNA Micelles for Sensitive Quantification of Biomarkers. Anal. Chem. 2023, 95, 1794−1800.

11.Lv, W. Y.; Li, C. H.; Yang, F. F.; Li, Y. F.; Zhen, S. J.*; Huang, C. Z.* Sensitive Logic Nanodevices with Strong Response for Weak Inputs. Angew. Chem. Int. Ed. 2022, e202115561. 

12.Yang F. F.; Li, C. H.; Lv, W. Y.; Zhen, S. J.*; Huang, C. Z.* Deoxyribonucleic Acid Photonic Wires with Three Primary Color Emissions for Information Encryption. Adv. Funct. Mater. 2021, 31, 2100322.

13.Li, C. H.; Lv, W. Y.; Yan, Y.; Yang F. F.; Zhen, S. J.*; Huang, C. Z.* Nucleolin-Targeted DNA Nanotube for Precise Cancer Therapy through For̈ster Resonance Energy Transfer-Indicated Telomerase Responsiveness. Anal. Chem. 2021, 93, 3526−3534.

14.Lv, W. Y.; Li, C. H.; Li, Y. F.; Zhen, S. J.*; Huang, C. Z.* Hierarchical Hybridization Chain Reaction for Amplified Signal Output and Cascade DNA Logic Circuits. Anal. Chem. 2021, 93, 3411−3417.

15.Zhen, S. J.*; Xiao, X.; Li, C. H.; Huang, C. Z. An Enzyme-Free DNA Circuit-Assisted Graphene Oxide Enhanced Fluorescence Anisotropy Assay for MicroRNA Detection with Improved Sensitivity and Selectivity. Anal. Chem. 2017, 89, 8766−8771.

16.Li, C. H.; Xiao, X.; Tao, J.; Wang, D. M.; Huang, C. Z.; Zhen, S. J.* A graphene oxide-based strand displacement amplification platform for ricin detection using aptamer as recognition element. Biosens. Bioelectron. 2017, 91, 149–154.

17.Du, Y.; Zhen, S. J.(共同一作); Li, B.; Byrom, M.; Jiang, Y. S.; Ellington, A. D. Engineering signaling aptamers that rely on kinetic rather than equilibrium competition. Anal. Chem. 2016, 88, 2250−2257.

18.Xiao, X.; Tao, J.; Zhang, H. Z.; Huang, C. Z.; Zhen, S. J.* Exonuclease III-assisted graphene oxide amplified fluorescence anisotropy strategy for ricin detection. Biosens. Bioelectron. 2016, 85, 822–827.

19.Xiao, X.; Li Y. F.; Huang, C. Z.*; Zhen, S. J.* A novel graphene oxide amplified fluorescence anisotropy assay with improved accuracy and sensitivity. Chem. Commun. 2015, 51, 16080−16083.

20.Zhen, S. J.; Chen, L. Q.; Xiao, S. J.; Li, Y. F.; Hu, P. P.; Zhan, L.; Peng, L.; Song, E. Q.; Huang, C. Z.* Carbon nanotubes as a low background signal platform for a molecular aptamer beacon on the basis of long-range resonance energy transfer. Anal. Chem. 2010, 82, 8432−8437.